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Reconstructing Historical Exposures to Respirable Dust and Respirable Silica in the Taconite Mining Industry for 1956-2010

机译:重建1956-2010年Taconite采矿业中可吸入粉尘和可吸入二氧化硅的历史暴露

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As part of ongoing epidemiological studies for assessing the association between exposure to taconite dusts and the development of respiratory diseases, the goal of our study is to reconstruct the historical silica (RS) and respirable dust (RD) exposures of workers in Minnesota taconite industry from 1955-2010 by developing a job exposure matrix (JEM) that uses 9,128 RS and 19,408 RD industrial hygiene monitoring data. Historical RS and RD data were obtained for seven taconite mines from three sources:(1) the Mine Safety and Health Administration (MSHA) has online database records for all inspection results since 1978 for 13 MSHA Mine IDs with 4,303 RD monitoring records;(2) the mining companies' internal monitoring reports provided 14,417 RD records, most of which date from the late 1970s.(3) University of Minnesota in 2010 conducted 688 pairs of RS and RD measurements covering six active mines. Unlike RD data which can be directly read from IH reports, many historical RS data have to be calculated using RD and silica percentage information. 8,840 RS data were calculated using available silica percentage information. After data treatment, all these data were grouped into 7 mines and then into 8 departments. Within each department, we applied a two-level random-intercept model which assumes that the natural log of Y (RD or RS) changes over time at a constant rate. Among the 56 mine-department combinations, 13 combinations show a significant (p-value<0.05) decreasing RS and RD trend with the maximum rate of decrease of 3.3% per year; 12 combinations show a significant increasing trend with the maximum annual increase rate of 8.7%. The estimated percent silica varies by department, with the maximum value usually occurring in the crushing department (8.5%-27.6%) and the minimum value occurring in the pelletizing department (2.6%-8.5%).The result of this study is a JEM by mine, department, and year for RD and RS that will form the basis for future epidemiological studies.
机译:作为正在进行的流行病学研究的一部分,以评估assess石粉尘暴露与呼吸系统疾病发展之间的关系,我们的研究目标是重建明尼苏达州con石粉行业工人的历史二氧化硅(RS)和可吸入粉尘(RD)暴露。 1955-2010年,通过开发使用9,128 RS和19,408 RD工业卫生监测数据的工作暴露矩阵(JEM)。从三个来源获得了7个ta石矿的RS和RD历史数据:(1)矿山安全与健康管理局(MSHA)拥有自1978年以来的所有检查结果的在线数据库记录,其中包含13个MSHA矿井ID和4,303个RD监测记录;(2 )矿业公司的内部监控报告提供了14,417 RD记录,其中大部分记录可追溯到1970年代后期。(3)明尼苏达大学在2010年进行了688对RS和RD测量,覆盖了六个活跃矿山。与可以直接从IH报告中读取的RD数据不同,必须使用RD和二氧化硅百分比信息来计算许多历史RS数据。使用可用的二氧化硅百分比信息计算出8,840个RS数据。经过数据处理后,将所有这些数据分为7个地雷,然后分为8个部门。在每个部门内,我们应用了两级随机拦截模型,该模型假设Y的自然对数(RD或RS)以恒定速率随时间变化。在56个矿山部门组合中,有13个组合显示RS和RD趋势显着(p值<0.05)下降,最大下降速度为每年3.3%。 12种组合呈显着增长趋势,最大年增长率为8.7%。估计的二氧化硅百分比因部门而异,最大值通常发生在破碎部门(8.5%-27.6%),最小值发生在制粒部门(2.6%-8.5%)。这项研究的结果是JEM按矿山,部门和年份划分RD和RS,这将成为未来流行病学研究的基础。

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