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Modelling and dynamics of intramammary infections caused by Corynebacterium species

机译:棒杆菌属细菌引起的乳房内感染的建模和动力学

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We present a deterministic mathematical model that describes the transmission dynamics of intramammary infections (IMI) caused by Corynebacterium spp. (Corynebacterium species) in lactating dairy herds. Longitudinal, quantitative, dynamic models are likely to be valuable for predicting infections outbreak risk, quantify the effectiveness of response tactics and performing response planning. Previous investigations on IMI have considered the transmission of several bacterial pathogens, but not Corynebacterium spp., in modelling investigations. We have established a new Corynebacterium spp. SIS compartmental model subject on appropriate unknown parameters that we estimated by using a deterministic approach, based on real data fitting procedure. The real data, from which the parameters of the model are estimated, were obtained in a field trial conducted in a New York dairy herd (US).
机译:我们提供了一种确定性数学模型,该模型描述了由棒杆菌属引起的乳内感染(IMI)的传播动力学。 (棒状杆菌属)在奶牛群中。纵向,定量,动态模型对于预测感染爆发风险,量化应对策略的有效性和执行应对计划可能很有价值。先前对IMI的研究在模型研究中已考虑了几种细菌病原体的传播,但未考虑棒状杆菌的传播。我们建立了一个新的棒杆菌属。 SIS隔室模型的主题是基于真实数据拟合过程的适当未知参数,我们通过确定性方法对这些未知参数进行了估计。在纽约奶牛场(美国)进行的现场试验中获得了估计模型参数的真实数据。

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