首页> 外文会议>Society for Biomaterials annual meeting and exposition >Syndecan-4 Proteoliposomes Enhance Cutaneous Wound Healing and Induce Neovascularization in Ischemic Limb in a Diabetic Hyperlipidemic Mouse
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Syndecan-4 Proteoliposomes Enhance Cutaneous Wound Healing and Induce Neovascularization in Ischemic Limb in a Diabetic Hyperlipidemic Mouse

机译:Syndecan-4蛋白脂质体增强糖尿病高脂血症小鼠缺血性肢体的皮肤伤口愈合并诱导新血管形成

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Taken together, these preliminary studies support that co-delivery of syndecan-4 with FGF-2 enhances both wound healing and neovascularization in a clinically relevant diseased mouse model. Our treatment restores the signaling pathway components that are lost due to diseased state causing tissues to become resistant to growth factor therapies.
机译:综上所述,这些初步研究支持在临床相关的患病小鼠模型中,将syndecan-4与FGF-2共递送可增强伤口愈合和新血管形成。我们的治疗可以恢复因患病状态而丢失的信号通路成分,从而导致组织对生长因子疗法产生抵抗力。

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