Additional Perspectives for Developing Consumer Exposure Estimates: Consumer Exposure Models and Public Data

摘要

Within the context of the ExpoDat program, multimedia models have been used to develop screening level consumer exposure estimates. Applying multimedia modeling approaches to consumer exposure assessment (nearfield exposure) is a fairly recent development in Exposure Sciences, and represents one of many approaches that can be used. A number of models specific to developing consumer exposure estimates from direct product use are also available, ranging from screening level to higher tier tools. Available models include ones that cover multiple types of consumer products as well as ones that are focused on a specific product type. The scientific underpinnings of two of the screening level models used in developing submissions under the EU Registration Evaluation and Authorization of Chemicals (REACH) regulation will be discussed: the European Center for Ecotoxicology and Toxicology Targeted Risk Assessment tool and the European Solvent Industry Group's Generic Exposure Scenario Risk and Exposure Tool. To better understand how different modeling approaches compare, results from the REACH screening models, the higher tier ConsExpo model, and available exposure measurements will be compared with ExpoDat multimedia model-based predictions.