Injectable PoIy(N-isopropylacrylamide)-grafted HA and Chitosan Hydrogel as a Barrier for Prevention of Postoperative Abdominal Adhesion in Laparoscopic Surgery

摘要

Through the combination of SLS manufacturing technology and surface modified PCL, we provide a report on the tissue engineering of cartilage for aesthetic reconstruction. SLS provides us with the ability to optimize macrostructure and geometry of the scaffold, and produces reproducible in scaffold characteristics. Surface modification of PCL can balance out the less ideal properties of the PCL material itself. Collagen as a surface modification material is superior to gelatin in terms of supporting cells growth and stimulating ECM protein secretion. With further adjustments in these parameters, an ideal scaffold for cartilage tissue engineering aimed at reconstructive purposes may be achieved.