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Feasible approach to control the operation of implantable rotary blood pumps for heart failure patients

机译:控制心力衰竭患者植入式旋转血泵操作的可行方法

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In order to assess left ventricular support in heart failure patients, a lumped parameter model of a rotary blood pump and the cardiovascular system was used to investigate different control strategies. In this paper, a sensor-less control strategy for a left ventricular assist device (LVAD) based on pulsatile flow estimation has been presented, which referred to the crucial issue in the usefulness of LVADs is how to control the operation of the pump rotational speed to cater for cardiovascular system perturbations and changing metabolic demand for heart failure patients. A tracking control algorithm based on a robust sliding mode technique was developed to track the error difference between the reference pump flow and estimated mean pulsatile flow. A lumped parameter model of cardiovascular system in combination with the stable dynamical model of pulsatile flow estimation was used to evaluate the controller. The control algorithm was tested using constant and sinusoidal reference pump flow inputs under healthy and heart failure conditions. Tracking control was illustrated in the presence of modeling uncertainty and disturbance. Simulation results demonstrated that the control algorithm was able to track the reference input with minimal error in the presence of model uncertainty.
机译:为了评估心力衰竭患者的左心室支持,使用旋转血泵和心血管系统的集总参数模型来研究不同的控制策略。本文提出了一种基于脉动流量估计的左心室辅助设备(LVAD)的无传感器控制策略,该方法提到了LVAD实用性中的关键问题是如何控制泵的转速运行以满足心血管系统的微扰和心力衰竭患者新陈代谢需求的变化。开发了基于鲁棒滑模技术的跟踪控制算法,以跟踪参考泵流量与估算的平均脉动流量之间的误差差。结合心血管系统的集总参数模型和脉动血流估计的稳定动力学模型来评估控制器。在健康和心力衰竭情况下,使用恒定和正弦参考泵流量输入对控制算法进行了测试。在存在模型不确定性和干扰的情况下说明了跟踪控制。仿真结果表明,在存在模型不确定性的情况下,该控制算法能够以最小的误差跟踪参考输入。

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