Optimization of Micro-Optical Dimensions for Enhancing Sensitivity in Integrated Microfluidic Laser-Induced Fluorescence Detection

摘要

A method to achieve a 2-fold increase in SNR by optimizing detector dimensions and microlens position is described. As a proof-of-concept microfluidic LIF-CE detection module, a micro-ball lens embedded in carbon-blackened PDMS filter is used to couple fluorescence to an on-chip CMOS detector.