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Chondroitin sulfate -Epidermal growth factor (EGF) coating for stent-grafts: versatility and optimization by oriented tethering

机译：硫酸软骨素-表皮生长因子（EGF）涂层，用于覆膜支架：多功能性和定向束缚优化

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We have created a bioactive anti-apoptotic coating that greatly improves VSMC growth and resistance to apoptosis. This coating has proven to be efficient on various polymeric substrates, including non-favorable PTFE. Moreover we have shown that to further optimize the coating, it is possible to immobilize EGF via coiled/coil tethering on CS.

机译：我们已经创建了一种具有生物活性的抗凋亡涂层，可以极大地改善VSMC的生长和对细胞凋亡的抵抗力。事实证明，这种涂层在各种聚合物基材（包括不利的PTFE）上都是有效的。此外，我们已经表明，为了进一步优化涂层，可以通过在CS上进行盘绕/线圈束缚来固定EGF。

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《World biomaterials congress》|2012年|805-805|共1页
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Pauline Lequoy; Houman Savoji; Cindy Charbonneau; Benoit Liberelle; Gregory deCrescenzo; Sophie Lerouge;
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专利

1. Additive Benefits of Chondroitin Sulfate and Oriented Tethered Epidermal Growth Factor for Vascular Smooth Muscle Cell Survival [J] . Pauline Lequoy, Beno?t Liberelle, Gregory De Crescenzo, Macromolecular bioscience . 2014,第5期

机译：硫酸软骨素和定向拴系表皮生长因子对血管平滑肌细胞存活的附加益处
2. Chondroitin Sulfate and Epidermal Growth Factor Immobilization after Plasma Polymerization: A Versatile Anti-Apoptotic Coating to Promote Healing Around Stent Grafts [J] . Charbonneau C., Ruiz J.-C., Lequoy P., Macromolecular bioscience . 2012,第6期

机译：血浆软骨素硫酸盐和表皮生长因子固定化后的血浆：多功能抗凋亡涂层，以促进支架移植物周围的愈合。
3. Stimulation of cell growth and resistance to apoptosis in vascular smooth muscle cells on a chondroitin sulfate/epidermal growth factor coating. [J] . Charbonneau C, Liberelle B, Hebert MJ, Biomaterials . 2011,第6期

机译：在硫酸软骨素/表皮生长因子涂层上刺激血管平滑肌细胞的细胞生长和抗凋亡。
4. Chondroitin sulfate -Epidermal growth factor (EGF) coating for stent-grafts: versatility and optimization by oriented tethering [C] . Pauline Lequoy, Houman Savoji, Cindy Charbonneau, World biomaterials congress . 2012

机译：支架移植物的软骨素硫酸盐 - 血管生长因子（EGF）涂层：通过取向束缚的多功能性和优化
5. Distribution of Bone Morphogenetic Proteins and BMP receptors in Osteochondromas and Modulation of Transforming Growth Factor-beta1 Actions by Heparan Sulfate and Chondroitin Sulfate in Normal Articular Cartilage. [D] . Cuellar, Araceli. 2014

机译：骨软骨瘤中骨形态发生蛋白和BMP受体的分布以及正常软骨中硫酸乙酰肝素和硫酸软骨素的转化生长因子-β1行为的调节。
6. Ovarian Cancer Cell Heparan Sulfate 6-O-Sulfotransferases Regulate an Angiogenic Program Induced by Heparin-binding Epidermal Growth Factor (EGF)-like Growth Factor/EGF Receptor Signaling [O] . Claire L. Cole, Graham Rushton, Gordon C. Jayson, 2014

机译：卵巢癌细胞硫酸乙酰肝素6-O-磺基转移酶调节由肝素结合表皮生长因子（EGF）样生长因子/ EGF受体信号转导的血管生成程序。
7. In Vitro and Pilot In Vivo Evaluation of a Bioactive Coating for Stent Grafts Based on Chondroitin Sulfate and Epidermal Growth Factor [O] . Pauline Lequoy, Houman Savoji, Bachir Saoudi, 2016

机译：基于软骨素硫酸软骨素和表皮生长因子的支架移植物生物活性涂层体外和飞行员体内的体外和飞行员

Chondroitin sulfate -Epidermal growth factor (EGF) coating for stent-grafts: versatility and optimization by oriented tethering

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