Transendocardial injection of myocardial matrix hydrogel improves cardiac function and prevents negative left ventricular remodeling in a porcine myocardial infarction model

摘要

The myocardial matrix hydrogel mimics the complex native ECM, is deliverable via catheter, improves post-MI cardiac function, and does not induce arrhythmias in a large animal pre-clinical model, thus demonstrating its clinical potential as a minimally invasive treatment for MI.