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Most relevant sources of indoor particles in children's rooms and respiratory health effects of size-segregated particles

机译:儿童房间室内颗粒物的最相关来源以及尺寸分离颗粒物对呼吸系统健康的影响

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Numerous epidemiological studies have provided evidence of an association between elevated outdoor particulate air pollution and adverse health effects. Young children typically spend majority of time at home and indoors. There is still limited knowledge on indoor particles sources and especially on their health effects. Even insights into the influence of differently sized indoor particles on human health are extremely rare. We studied these correlations for three year aged children. Information on possible particle sources (exposure to environmental tobacco smoke, type of heating, and traffic at place of residence as well as in front of the children's room) and respiratory outcomes were obtained from questionnaires. Short-term measurements of particle mass and number concentrations within different particle size fractions were carried out in children's rooms. Indoor concentrations of these size fractions were correlated with possible sources of indoor particles and with respiratory health impacts. Daily smoking, smoking more than 5 cigarettes per day at home and traffic density in front of the window of children's room were found to be related to indoor exposure by particles of different diameters. High indoor particle exposures were associated with an increased risk for the development of obstructive bronchitis and in some extent of non-obstructive bronchitis. The strongest impact was associated to mass concentration of particles < 1 μm and the number concentration of particles > 0.5 μm. The risk increases still remain significant if tested for stability changing the number of adjustment variables or omitting randomly selected cases, respectively. Our results show significant associations between exposure to differently sized indoor particles and the risks for respiratory diseases in young children. Short-term measurements within epidemiological studies can help to assess the health risks of indoor particles with different sizes.
机译:大量的流行病学研究提供了证据,表明室外颗粒物空气污染加剧与不良健康影响之间存在关联。幼儿通常会在家里和室内度过大部分时间。关于室内颗粒物来源,尤其是其对健康的影响的知识仍然有限。甚至对于不同尺寸的室内颗粒对人体健康的影响的见解也极为罕见。我们研究了三岁儿童的这些相关性。从调查表中获取了有关可能的颗粒物来源(暴露于环境烟草烟雾,加热类型,居住地以及在儿童房间前的交通情况)和呼吸道结果的信息。在儿童房中对颗粒大小和不同粒径分数内的数浓度进行了短期测量。这些大小部分的室内浓度与室内颗粒的可能来源以及对呼吸健康的影响有关。人们发现,每天吸烟,每天在家中抽5支以上的香烟以及儿童房间窗户前的交通密度与室内暴露的直径不同的颗粒有关。室内高颗粒物暴露与阻塞性支气管炎发展的风险增加有关,在某种程度上与非阻塞性支气管炎有关。最强烈的影响与<1μm的颗粒质量浓度和> 0.5μm的颗粒数浓度有关。如果进行稳定性测试,分别更改调整变量的数量或省略随机选择的案例,则风险增加仍然显着。我们的结果表明,暴露于不同尺寸的室内颗粒与幼儿呼吸系统疾病的风险之间存在显着关联。流行病学研究中的短期测量可以帮助评估不同大小的室内颗粒的健康风险。

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