Stability and Hopf Bifurcation in a Viral Infection Model with Immune Impairment and Delayed Immune Response

摘要

A viral infection model with immune impairment and delayed immune response is investigated.The model may exhibit a bistable behavior in some parameter regions, which means that infection will result in disease or immune control outcome, depending on the initial conditions. Furthermore, the existence of Hopf bifurcations at the immune control equilibrium is also studied. Numerical simulations are carried out to illustrate the main results.