Construction optimization of the sensors used in point fluorescence investigation of cancer-changed tissues

摘要

Fluorescence is a known phenomenon used in different fields of research. For the purpose of this study, different types of fiber optic sensors were used to investigate cancerous tissues with one photon fluorescence. Several probes were tested in terms of their sensitivity and efficiency of resulting measurements. The obtained fluorescence spectral characteristics, with intensity peaks typically falling in 480-520nm range, outlined clearly pathologically changed areas. The intensity of detected fluorescence determines the evaluation of disease advancement.