CHARACTERIZATION OF DYSFUNCTION IN LEFT AND RIGHT TEMPORAL LOBES OF ANXIETY PATIENTS: USING SPATIOTEMPORAL LYAPUNOV EXPONENT

摘要

The dysfunction in anxiety disease has been widely observed in clinics, but the underlying neural mechanism is not yet well understood. Function MRI data were collected conventionally ''imperfectly'' with low frequency and short scans when participants were processing our experimental tasks. In order to find the nonlinear differences, we here propose the spatiotemporal Lyapunov exponent as a quantitative measure. Our result reveals that there are significant differences between the two groups. We conclude that: (1) spatiotemporal Lyapunov exponent could be used to explore nonlinear character of conventional ''imperfect'' fMRI data; (2) the abnormal nonlinear dynamic behavior exists in bilateral temporal lobes when patients are taking our experimental tasks.