Abstract: The image quality in optical imaging is actually under intense investigation in order to ultimately define the role of optical techniques for medical diagnosis purposes. In this work we have investigated the spatial resolution, noise and contrast parameters by using edge response function measurements with masks having well-controlled optical properties. The experimental set-up mainly consisted of an Argon pumped Titanium-Sapphire laser working in femtosecond regime and a streak camera with a few picosecond of temporal resolution. The investigated samples were solutions of Intralipid 10% with distilled water in order to approximate optical properties of biological tissues. The experimental data were analyzed with different imaging algorithms and compared with theoretical predictions about the above- mentioned image quality parameters. The use of spatial resolution, contrast and signal-to-noise ratio allowed us in identifying the best working conditions for optical imaging systems and in evaluating the efficiency of different image reconstruction algorithms. !23
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