Evidence of Scale-Free Topology and Dynamics in Gene Regulatory Networks

摘要

Temporal gene expression data (Wen, et. al.) was analyzed using the recently introduced inverse modeling technique of Embedded Complex Logistic Maps (ECLM). Preliminary results indicate a scale-free structure in the gene regulatory network topology and the network's energy dissipation characteristics. General agreement was found with other recent studies using dynamical models and connectivity analysis of other biochemical networks. The highlights of our study are briefly outlined.