Chemical dissolution and bone formation in identical porous β-TCP and HA

摘要

Porosity and macroporosity in porous calcium phosphate bioceramics play an important role in conducting cells and vessels penetrating into pores and forming bone ingrowth inside bioceramics. Histological results indicated new bone volume (NBV) was higher in β-tricalcium phosphate (β -TCP) implants than that in hydroxyapatite (HA) implants for identical porosity of 75% at both 1 month and 3 months, and the degradation of β -TCP was too quick to keep its original shape at 3 month. According to the XRD analysis, chemical dissolution seemed to be one part of degradable mechanism for β-TCP.