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Design and Validation of a Tremor Stabilizing Handle for Patients with Parkinson Disease and Essential Tremor

机译:帕金森病和原发性震颤患者的震颤稳定手柄的设计和验证

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Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by resting tremor and postural instability. Essential Tremor (ET) disease is another neurological disorder which causes involuntary and rhythmic shaking of the hands and other body parts and affects about 10% of all Americans. The degradations of motor skills severely affect daily activities of patients such as eating, writing and dressing. Existing pharmacological treatments, in general, have shown side effects over long term. In recent years, wearable devices and stabilizing assistive devices have been developed to address uncontrolled tremor. The products have shown great potential, but they are not ideal yet. In this work, we developed a low-cost noninvasive handle stabilizing to a preferred orientation in the presence of hand tremors. A validation study evaluated the performance of this prototype on a vibration generator that simulates specific vibrations relevant for PD and ET. The results show that the presented tremor reduction system controls external vibration better than the on-market products. The prototype also has a significantly lower cost and lighter weight. With these combined advantages, this work may help people with PD and ET accomplishing fine motor tasks and therefore improve the quality of life for this unattended population.
机译:帕金森氏病(PD)是第二大最常见的神经退行性疾病,其特征是静息性震颤和姿势不稳。原发性震颤(ET)病是另一种神经系统疾病,可引起手和身体其他部位的不自主和有规律的晃动,并影响了约10%的美国人。运动能力的下降严重影响患者的日常活动,如进食,写字和穿衣。通常,现有的药物治疗长期显示出副作用。近年来,已开发出可穿戴设备和稳定辅助设备以解决不受控制的震颤。这些产品已显示出巨大的潜力,但还不理想。在这项工作中,我们开发了一种低成本的无创手柄,可在手震的情况下稳定到首选方向。一项验证研究在振动发生器上评估了该原型的性能,该振动发生器模拟了与PD和ET相关的特定振动。结果表明,与市场上出售的产品相比,所提出的减震系统能够更好地控制外部振动。该原型还具有明显更低的成本和更轻的重量。有了这些综合的优势,这项工作可以帮助PD和ET的人完成精细的运动任务,从而改善这一无人看管的人群的生活质量。

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