Free-Form Deformations Using Adaptive Control Point Status for Whole Heart MR Segmentation

摘要

Whole heart segmentation from cardiac MRI is useful in clinics but challenging due to the large shape variation of the heart and many indistinct boundaries commonly presented in the MR images, especially in pathological cases. Image registration for whole heart MR images has been developed and applied to atlas propagation based segmentation [1]. In this paper, we base on this segmentation framework and propose a new non rigid registration, a free-form deformations (FFDs) registration using adaptive control point status, for the segmentation refinement. This method activates and optimises control points according to the combined information of the deformation field and the heart surface from the atlas to improve the registration performance. The segmentation framework using this registration demonstrates a RMS accuracy of 1.8 ± 0.2 mm in 10 pathological data.