SCREENING OF BISPHENOL A AND ITS HALOGENATED ANALOGUES IN SURFACE WATER BY COMBINATION OF PSEUDO-MOLECULARLY IMPRINTED SPE AND LIQUID CHROMATOGRAPHY

摘要

This study highlighted the potential of pseudo molecularly imprinted polymer (MIP) for simultaneous extraction of trace bisphenol A (BPA) and its halogenated analogues in surface water. Bisphenol E (BPE) was selected as the pseudo template and the resulting MIP showed appropriate selectivity for other bisphenols, avoiding the interferences originated from the template leakage. Pseudo MISPE-HPLC method was established and then validated with linearity, precision, limit of detection (LOD) and recoveries. LOD for each bisphenol compound was 2.5 -10 ng/L. The proposed method is suitable for highly selective and sensitive detection of trace bisphenols in environmental samples, and a promising approach for environmental monitoring.