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Carboxymethyl Starch Derivatives as Excipients Affording Resistance to Gastric Acidityfor Escherichia coli Oral Formulations

机译：羧甲基淀粉衍生物作为赋形剂，可抵抗大肠杆菌口服制剂对胃酸的抵抗性

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Carboxymethyl high amylose starch (CM-HAS) isproposed as excipient for oral tablet formulation ofbioactive agents. The bacteria (lyophilizedEscherichia coli) thus formulated displayed highersurvival rates in acidic conditions and for longerperiods than the free bacteria or than the bacteriaformulated with the non-derivatived starch.

机译：羧甲基高直链淀粉（CM-HAS）被提议作为生物活性剂口服片剂制剂的赋形剂。如此配制的细菌（冻干的大肠杆菌）在酸性条件下显示出更高的存活率，并且其周期比游离细菌或非衍生淀粉配制的细菌更长。

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来源
《Controlled Release Society annual meeting》|2004年|1-2|共2页
会议地点 Honolulu, HI(US)
作者
Carmen Calinescu; Jér?me Mulhbacher; éric Nadeau; John Fairbrother; Mircea-Alexandru Mateescu;
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Department of Chemistry and Biochemistry Université du Québec à Montréal Québec Canada H3C 3P8carmen_calinescu @canada.com;

Department of Chemistry and Biochemistry Université du Québec à Montréal Québec Canada H3C 3P8;

Faculté de médecine vétérinaire Université de Montréal Saint-Hyacinthe Québec Canada J2S 7C6;

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1. Carboxymethyl high amylose starch (CM-HAS) as excipient for Escherichia coli oral formulations. [J] . Calinescu C, Mulhbacher J, Nadeau E, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2005,第1期

机译：羧甲基高直链淀粉（CM-HAS）作为大肠杆菌口服制剂的赋形剂。
2. Carboxymethyl-Starch Excipients for Gastrointestinal Stable Oral Protein Formulations Containing Protease Inhibitors [J] . Patrick De Koninck, Denis Archambault, Francine Hamel, Journal of Pharmacy and Pharmaceutical Sciences . 2010,第1期

机译：含有蛋白酶抑制剂的胃肠道稳定口服蛋白质制剂的羧甲基淀粉赋形剂
3. High-amylose sodium carboxymethyl starch matrices for oral, sustained drug-release: Formulation aspects and in vitro drug-release evaluation. [J] . Brouillet F, Bataille B, Cartilier L International Journal of Pharmaceutics . 2008,第1a2期

机译：用于口服，持续药物释放的高直链淀粉羧甲基淀粉钠基质：配方方面和体外药物释放评估。
4. Carboxymethyl Starch Derivatives as Excipients Affording Resistance to Gastric Acidity for Escherichia coli Oral Formulations [C] . Controlled Release Society annual meeting . 2004

机译：羧甲基淀粉衍生物作为赋形剂，这是对大肠杆菌口服配方的抗胃酸耐性
5. High-amylose carboxymethyl starch matrices for oral sustained drug-release: In vitro and in vivo evaluation. [D] . Domingues Nabais, Maria Teresa. 2014

机译：用于口服持续药物释放的高直链淀粉羧甲基淀粉基质：体外和体内评估。
6. Self-stabilized chitosan and its complexes with carboxymethyl starch as excipients in drug delivery [O] . Mihaela Leonida, Pompilia Ispas-Szabo, Mircea Alexandru Mateescu 2018

机译：自稳定壳聚糖及其与羧甲基淀粉的复合物作为赋形剂在药物递送中的作用
7. Synthesis and evaluation of the structural and physicochemical properties of carboxymethyl pregelatinized starch as a pharmaceutical excipient [O] . Lefnaoui Sonia, Moulai-Mostefa Nadji 2015

机译：羧甲基预糊化淀粉作为药物赋形剂的合成及结构和理化性质的评估

Carboxymethyl Starch Derivatives as Excipients Affording Resistance to Gastric Acidityfor Escherichia coli Oral Formulations

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