Clinically-compatible time-resolved diffuse spectroscopy in the 600-1100 nm bandwidth

摘要

We describe the development of a compact time-resolved system for the measurement of the optical properties of highly scattering media over a bandwidth of 600-1100 nm. The instrument is based on a fiber laser generating supercontinuum radiation, that is spectrally dispersed and used to sequentially illuminate the sample. A single photon avalanche photo-diode in combination with time correlated single-photon counting is used to recover the time-dispersion curve at each wavelength. The calibration of the system and in-vivo applications are shown.