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High-resolution DMD-FPM system based on ring pattern phase retrieval algorithm

机译:基于环形相位检索算法的高分辨率DMD-FPM系统

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We report an approach to enhance the resolution of the microscopy imaging by using the fourier ptychographic microscopy (FPM) method with a laser source and Spatial Light Modulator (SLM) to generate modulated sample illumination. The performance of the existed FPM system is limited by low illumination efficiency of the LED array. In our prototype setup, digital micromirror device (DMD) is introduced to replace the LED array as a reflective spatial light modulator and is placed at the front focal plane of the 4F system. A ring pattern sample illumination is generated by coding the micromirrors on the DMD, and converted to multi-angular illumination through the relay illumination system. A series of intensity sample images can be obtained by changing the size of the ring pattern and then used to reconstruct high resolution image through the ring pattern phase retrieval algorithm. Finally, our method is verified by an experiment using a resolution chart. The results also show that our method have higher reconstruction resolution and faster imaging speed.
机译:我们报告了一种方法,该方法通过与激光源和空间光调制器(SLM)一起使用傅立叶色谱分析(FPM)方法来产生调制的样品照明,从而提高显微镜成像的分辨率。现有的FPM系统的性能受到LED阵列的低照明效率的限制。在我们的原型设置中,引入了数字微镜器件(DMD)来代替LED阵列作为反射式空间光调制器,并将其放置在4F系统的前焦平面上。通过在DMD上对微镜进行编码来生成环形图案照明,然后通过中继照明系统将其转换为多角度照明。通过更改环形图案的大小可以获得一系列强度样本图像,然后通过环形图案相位检索算法将其用于重建高分辨率图像。最后,通过使用分辨率图表的实验验证了我们的方法。结果还表明,该方法具有更高的重建分辨率和更快的成像速度。

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