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Au Nanoparticle-based Detection of Human Chorionic Gonadotropin Using Electrochemical Impedance Spectroscopy

机译:基于金纳米粒子的人绒毛膜促性腺激素的电化学阻抗谱检测。

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摘要

A disposable screen-printed carbon electrode (SPCE) for point-of-care detection platform was developed for human chorionic gonadotropin (hCG). A sandwich-assay employing gold nanoparticles was characterized with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). hCG was analyzed between 100 pg/mL and 1 ng/mL, and a detection limit of 100 pg/mL was observed with 2-μL sample volume. This versatile platform can be easily adapted for decentralized electrochemical immunosensing of clinically important hormones.
机译:为人类绒毛膜促性腺激素(hCG)开发了用于即时检测平台的一次性丝网印刷碳电极(SPCE)。采用金纳米颗粒的夹心测定通过差分脉冲伏安法(DPV)和电化学阻抗谱(EIS)进行了表征。在100 pg / mL和1 ng / mL之间分析了hCG,在2 µL样品体积中观察到的检出限为100 pg / mL。这个多功能平台可以轻松地用于临床重要激素的分散电化学免疫传感。

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  • 会议地点 Honolulu HI(US)
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    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

    Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada;

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