ANALYSIS OF DEFORMATION PROCESS OF A BUBBLE IN A CELL MODEL BY SHOCK WAVE FOR DEVELOPING DRUG DELIVERY SYSTEMS

摘要

This paper describes the trial of making microcapsules and deformation analysis of a bubble near the curved elastic wall using macro 2d model and plane shock wave. The prototype microcapsules are made by using micromanipulation systems. It is found that by controlling the initial position of a bubble from the wall and the curvature of the wall there is a point to have large deformation, which tends to be collapsed easily. This is one of the results to aid design of DDS or bioprocess for cell-integration.