The Influence of Hydrophilic Pore Formers on Metoprolol Succinate Release from Mini-tabs Coated with Aqueous Ethylcellulose Dispersion

机译：亲水性孔形成剂对琥珀酸美托洛尔从水性乙基纤维素分散液包被的小片中释放的影响

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This study investigated the influence of incorporating a water-soluble pore former (based on polyvinyl alcohol; PVA) into aqueous ethylcellulose dispersion (Surelease ) film coating on in vitro release of a model drug, metoprolol succinate, from mini-tabs.

机译：这项研究调查了将水溶性成孔剂（基于聚乙烯醇； PVA）掺入乙基纤维素水分散体（Surelease）薄膜包衣中对从微型标签体外释放模型药物琥珀酸美托洛尔的影响。

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《Annual meeting exposition of the Controlled Release Society》|2010年|p.1013-1014|共2页
会议地点 Portland OR(US)
作者
Hue Vuong; Marina Levina; Tom Farrell; AN R. Rajabi-Siahboomi;
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Colorcon Limited Flagship House Victory Way Crossways Dartford DA2 6QD UK;

Colorcon Inc. Haiieysville PA USA;

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1. Novel ethylcellulose-coated pellets for controlled release of metoprolol succinate without lag phase: characterization, optimization and in vivo evaluation [J] . Wang Yuli, Yang Jiahui, Qian Yong, Drug development and industrial pharmacy . 2015,第7a12期

机译：新型乙基纤维素包衣的小丸，用于无延迟阶段的控释琥珀酸美托洛尔的释放：表征，优化和体内评估
2. Ibuprofen release kinetics from controlled-release tablets granulated with aqueous polymeric dispersion of ethylcellulose II: Influence of several parameters and coexcipients [J] . Khan GM., Zhu JB. Journal of Controlled Release: Official Journal of the Controlled Release Society . 1998,第1a3期

机译：布洛芬从乙基纤维素水性聚合物分散体制粒的控释片剂中的释放动力学：几个参数和辅料的影响
3. Modulation of drug (metoprolol succinate) release by inclusion of hydrophobic polymer in hydrophilic matrix. [J] . Siddique S, Bose A, Khanam J Drug development and industrial pharmacy . 2011,第9期

机译：通过在亲水性基质中包含疏水性聚合物来调节药物（琥珀酸美托洛尔）的释放。
4. Adjustment of Desired Drug Release Patterns From Pellets Coated With Aqueous Ethylcellulose Dispersions: Importance of the Type of Core and Drug Solubility [C] . Susanne Muschert, Florence Siepmann, Bruno Leclercq, Controlled Release Society Annual Meeting and Exposition . 2007

机译：从乙基纤维素水分散体包衣的药丸中所需药物释放模式的调整：核心类型和药物溶解度的重要性
5. Characterization of metoprolol succinate coated with Surelease(TM) polymer and fluid bed monitoring using NIR. [D] . Enagbare, Blessing O. 2009

机译：涂有Surelease™聚合物的琥珀酸美托洛尔的表征，并使用NIR监测流化床。
6. Model Drug as Pore Former for Controlled Release of Water-Soluble Metoprolol Succinate from Ethylcellulose-Coated Pellets Without Lag Phase: Opportunities and Challenges [O] . Yuli Wang, Jingjing Dai, Xinyi Chang, 2015

机译：从无纤维素相的乙基纤维素包衣小丸中控释水溶性琥珀酸美托洛尔琥珀酸酯的前药模型药物：机遇与挑战
7. Model Drug as Pore Former for Controlled Release of Water-Soluble Metoprolol Succinate from Ethylcellulose-Coated Pellets Without Lag Phase: Opportunities and Challenges [O] . Yuli Wang, Jingjing Dai, Xinyi Chang, 2014

机译：模型药物作为孔前的孔隙以供水溶性美托洛尔琥珀酸酸脱落的甲基纤维素染色的颗粒，没有滞后阶段：机会和挑战
8. Physical Oceanographic Characteristics Influencing the Dispersion of Dissolved Tracers Released at the Sea Floor in Selected Deep Ocean Study Areas [R] . Kupferman, S. L., Moore, D. E. 1981

机译：物理海洋学特征影响深海研究区海底释放的溶解示踪剂的分散

The Influence of Hydrophilic Pore Formers on Metoprolol Succinate Release from Mini-tabs Coated with Aqueous Ethylcellulose Dispersion

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