In vivo monitoring the intraocular pressure of anterior chamber in normal rabbits

摘要

To develop a method to monitor the intraocular pressure (IOP) of the anterior chamber in vivo in normal rabbits, to observe the value of the normal IOP, and to detect the distribution regularity in the 24 hours of normal rabbits. Normal IOP was monitored in 15 New Zealand white rabbit eyes. The measurements of IOP of all the experimental rabbits were by Millar transducer which was embedded in the anterior chamber. The analog signal of IOP was filtered, amplified and transformed into digital signal by Powerlab system, and was real-time displayed by Chart software. We successfully obtained the IOP value of 7 anterior chamber groups. The IOP of anterior chamber was (1.31±0.21～2.74±0.83)KPa. The distribution was as follows: the value of the IOP was lower from 0:00 to 5:00 and from 18:00 to 23:00 and gradually increased from 5:00 to 10:00.The peak value of the anterior chamber was at 11:00 and 17:00.The results suggest that we develop a convenient, feasible method to monitor the IOP of rabbits.