methods for increasing the antigenic mass of a leptospira culture and for producing a leptospirosis vaccine, leptospira culture, leptospirosis vaccine, and uses of a leptospira culture and a compound or composition

摘要

1/1 summary "methods" for increasing the antigenic mass of a leptospira culture and for producing a leptospirosis vaccine, leptospira culture, leptospirosis vaccine, and uses of a leptospira culture and a compound or composition. The antigenic mass of leptospira cultures can be significantly increased, regardless of any increase in biomass, by supplementing leptospira cultures with a specific type of fatty acid, a polyunsaturated c18 fatty acid. This provides advantages in the production of leptospira antigens. This also allows the production of improved leptospirosis vaccines, which are safer and more effective.