IRMPD Spectroscopy Shows That AGG Forms an Oxazoione b2+ Ion

摘要

The determination of structural features at the molecular level can provide fundamental insights into the activity, behavior, and function of biological systems. While techniques such as NMR and X-ray crystallography have stood as benchmarks for determining biological structure, mass spectrometry is playing an increasing role in investigating structural features,1 2 With the advent of soft ionization techniques such as MALDI and ESI, biological systems from small molecules to peptides to macromolecular protein complexes can be examined using a range of mass spectrometric techniques.3 Because analysis occurs in a solvent-free environment, mass spectrometry also introduces the opportunity to examine intrinsic features and interactions that may not be present in an aqueous solvent system.