Catalytic C-H Amination for the Preparation of Substituted 1,2-Diamines

摘要

Vicinal diamines appear frequently as structural units in biological and medicinal molecules of interest and as auxiliary groups or ligands for catalytic processes. The rich and varied applications for 1,2-diamines belie the rather modest number of general methods for the efficient preparation of such compounds. Accordingly, we have attempted to capitalize on the power of sulfamate ester C-H amination to address this problem (Figure 1).