Mechanistic Study of Samarium Diiodide-HMPA Initiated 5-exo-trig Ketyl-Olefin Coupling: The Role of HMPA in Post-Electron Transfer Steps

摘要

One of the most important follow-up steps in the reduction of ketones by samarium diiodide (SmI_2) is addition of a ketyl radical to an olefin. Intramolecular ketyl-olefin and related coupling events provide routes to a range of important intermediates an