Asymmetric Synthesis of (-)-lncarvillateine Employing an Intramolecular Alkylation via Rh-Catalyzed Olefinic C-H Bond Activation

摘要

(-)-Incarvillateine, (-)-1, is a monoterpene alkaloid that has attracted attention due to its potent analgesic properties. The first enantioselective synthesis of this natural product was recently achieved but required a number of steps to correctly set t