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首页> 外文期刊>Journal of the American Chemical Society >Invention of the First Azo Compound To Serve as a Superoxide Thermal Source under Physiological Conditions: Concept, Synthesis, and Chemical Properties
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Invention of the First Azo Compound To Serve as a Superoxide Thermal Source under Physiological Conditions: Concept, Synthesis, and Chemical Properties

机译:在生理条件下用作超氧化物热源的第一种偶氮化合物的发明:概念,合成和化学性质

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摘要

In summary, the invention of SOTS-1 provides a unique and novel tool for investigating superoxide-dependent oxidative stress under well-defined, metal ion free, biomimetic conditions. We are currently comparing the effect of equal fluxes of Superoxide from SOTS-1 and the aerobic XO/AA couple on Strand scission of Escherichia coli plasmid DNA (both super- Coiled and a short linear restriction fragment).
机译:总之,SOTS-1的发明提供了一种独特且新颖的工具,用于研究在明确定义的,无金属离子的仿生条件下的超氧化物依赖性氧化应激。我们目前正在比较来自SOTS-1和好氧XO / AA对的超氧化物等通量对大肠杆菌质粒DNA(超螺旋和短线性限制片段)断裂的影响。

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