Circulating and Synovial Fluid Heat Shock Protein 70 Are Correlatedwith Severity in Knee Osteoarthritis

摘要

Heat shock proteins are molecules rapidly produced under conditions ofenvironmental stress, and involve in protecting the cells structuralintegrity and function. Osteoarthritis (OA) is a chronic destructivedisorder of the joints manifested by the ongoing deterioration and loss ofarticular cartilage. The present study aimed to analyze circulating andsynovial heat shock protein (Hsp70) values in knee osteoarthritis patientsand healthy controls and to determine their relationship with theradiographic grading of the severity of knee OA.